My all-time favorite Chicken and Noodle Casserole. It’s a super creamy, cheesy pan of deliciousness that is quick and easy to put together!

Chicken and Noodles Casserole 1

After many years of making this myself for my family, it is now one of my favorite comfort foods!  I love it’s super creamy texture and the onion and mushroom combo flavor the sauce perfectly.  Whenever the weather has been cold for too long, or I’m feeling blue or things are super stressful, this is where I turn.  When the whole family is back together and we want something everyone likes this is a go-to recipe.   I know it’s a simple dish but somehow it transcends all that and just makes darn near everything better.

Good news! It’s quick and easy to fix and will feed a family of 6. Now, for the one little piece of info that some foodies might object to….the sauce is made with canned soup. Oh, for heaven sake, get over it!  There’s absolutely no shame!!!  Just enjoy this delicious pan of lovin’ from the oven!
Chicken and Noodles Casserole

How To Make Chicken Noodle Casserole


3.9 from 28 votes

Grandma's Chicken and Noodle Casserole

My all-time favorite Chicken and Noodle Casserole. It's a super creamy, cheesy pan of deliciousness that is quick and easy to put together!

Prep Time 10 minutes
Cook Time 30 minutes
Total Time 40 minutes
Servings 8
Calories 518 kcal
Author Kathleen


  • 8 Ounces Dried Spaghetti
  • 2 Tablespoons Butter
  • 1 1/2 Cups Fresh Mushrooms Sliced
  • 1/2 Cup Yellow Onion Finely Chopped
  • 2 10.75 Ounces Cans Condensed Cream of Chicken Soup
  • 1 Cup Sour Cream
  • 1 Cup Sharp Cheddar Cheese Shredded
  • 1 Fully Cooked Rotisserie Chicken Shredded


  1. Preheat oven to 350 degrees.
  2.  Cook pasta according to package directions until just al dente. Drain and set aside.
  3. In a saucepan, melt butter then saute mushrooms and onion until both are nice and soft.
  4. In a large bowl mix soup and sour cream until blended. And cooked mushrooms, onion, chicken and spaghetti and fold until everything is evenly coated with sauce.

  5. Pour spaghetti into a 9x13 dish and top with cheese. Bake in a preheated oven for about 30 minutes or until casserole is heated through.

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Nutritional Information

Nutrition information will vary based on the specific products. To be safe, check the nutrition facts labels of your products. Optional object listed above have been left out of nutritional data.

Nutrition Facts
Grandma's Chicken and Noodle Casserole
Amount Per Serving
Calories 518 Calories from Fat 261
% Daily Value*
Total Fat 29g 45%
Saturated Fat 12g 60%
Cholesterol 128mg 43%
Sodium 228mg 10%
Potassium 442mg 13%
Total Carbohydrates 23g 8%
Dietary Fiber 1g 4%
Sugars 2g
Protein 37g 74%
Vitamin A 10.2%
Vitamin C 1.7%
Calcium 15.6%
Iron 11.8%
* Percent Daily Values are based on a 2000 calorie diet.

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